Lifestyle

Scientists leverage interference between signaling pathways for cancer treatment

In order for cancer to form in the human body, normal cells must acquire multiple mutations before they develop toward the disease. It was previously believed that these mutations acted in concert in the progression of cancer. But a new Nature study led by City of Hope’s Markus Müschen, M.D., Ph.D., chair of the Department […]

Lifestyle

Will your brain stay sharp into your 90s? certain factors are key

Some people in their 90s stay sharp whether their brain harbors amyloid protein plaques—a hallmark of Alzheimer’s disease—or not, but why? That’s the question researchers sought answers for among 100 people without dementia, average age 92, who were followed for up to 14 years. Their answer? A combination of genetic luck and a healthy, fulfilling […]

Lifestyle

Reduced-dose prasugrel efficacious for acute coronary syndrome

For elderly or low-weight patients with acute coronary syndrome (ACS), a reduced dose of prasugrel is efficacious compared with ticagrelor, according to a study published online July 21 in the Annals of Internal Medicine. Maurizio Menichelli, M.D., from Ospedale Fabrizio Spaziani in Frosinone, Italy, and colleagues conducted a prespecified analysis of 3,997 patients with ACS […]

Lifestyle

Novel therapeutic approaches for aggressive bone cancer

Osteosarcoma (OS) is the most common form of aggressive bone cancer. A MedUni Vienna study led by geneticist Erwin Wagner has uncovered new insights into the disease mechanisms of OS, paving the way for potential new diagnostic and treatment strategies for fighting the bone disease. The study has just been published in the high impact […]

Lifestyle

Antidepressant does not improve post-stroke recovery

The antidepressant fluoxetine has been suggested as a means to improve brain recovery after acute stroke. However, a large randomized study on stroke patients at 35 Swedish hospitals shows that the drug has no such effect. The study, which was led by researchers at Karolinska Institutet, is published in The Lancet Neurology. Every year almost […]

Lifestyle

World’s smallest imaging device has heart disease in focus

A team of researchers led by the University of Adelaide and University of Stuttgart has used 3-D micro-printing to develop the world’s smallest, flexible scope for looking inside blood vessels. The camera-like imaging device can be inserted into blood vessels to provide high quality 3-D images to help scientists better understand the causes of heart […]

Lifestyle

Interaction dynamics between designer microrobots and the immune system

Mobile medical microrobots can now be engineered in the lab for broad ranging applications from personalized disease treatment to targeted drug delivery. During their structural design, bioengineers aim to minimize physical interactions with cells of the immune system by optimizing the morphology (shape) of the device and its surface chemistry. It is therefore important to […]